I’ve held off for a little while from posting I really don’t want to jinx my progress. I’ ve been dealing with hormonal cystic acne since I was about. Spironolactone is a synthetic steroidal drug that causes loss of libido, depression, and fatigue. It masks symptoms but doesn’t solve any. Many cases of acne are hormonal in nature, meaning that they occur in adolescent girls and women and are aggravated by hormonal fluctuations such as those.

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Clinical Pharmacology and Therapeutics. I appreciate the info that you share. Can you please share with my readers whether you were ever able to come off it again? The initial response was dizziness, fatigue, and irritability. The evolution of aldosterone antagonists.


And just to clarify, spironolactone is not an estrogen therapy. Plus, since my testosterone is so low, it seems odd to take something espironolqctona is targeting that. I have been taking spiralatone for over a yr for my adult acne that I have suffered forever with after trying so many things this really works for me. Androgen excess in espirojolactona However, many patients have no signs of peripheral hyperandrogenism other than acne. I actually had miraculous reults with spironolactone and I was on the drug for 15 years for hirsutism and hair loss.

If you have been on it 3 months, your skin should have improved by now, assuming that you are ovulating regularly and have a good progesterone reading.

Do you have espigonolactona recommendations for getting off spiro? I hate this drug….

Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review

I only wish it was as easy as, just gain weight, but for women there is a lot of stigma with weight gain. However, the espironolactonx commonly prescribed regimen is mg daily for the initial treatment of hirsutism and mg daily for maintenance therapy. Aside from hyperkalemia, spironolactone may rarely cause severe side effects such as anaphylaxiskidney failurehepatitis two reported cases, neither serious[] agranulocytosisDRESS syndromeStevens—Johnson syndrome or toxic epidermal necrolysis.


I need to get rid of my hormonal acne.

Spironolactone: Is It Really the Safe Drug for Hormonal Hair Loss?

Two studies made apparently contradictory observations in respect of the efficacy of spironolactone against comedonal non-inflamed lesions. Can you please share the link? My progesterone is to the point where I could be considered perimenopausal. Spironolactone has antiandrogenic activity. Data for the first phase, which would be free of any potential carryover effects, were not reported.

The incidence appeared significantly lower when spironolactone was combined with a COC: Could the Spiro be the cause of this? Cutting dairy helped too though, as did primrose oil.

Spironolactone Reviews –

Never had hormone levels checked. I have very low progesterone, and low estrogen, and my dhea is mid range wcne I had been on the pill for over 20 years, and the shedding started slowly, but seems to correspond to getting off the pill and perimenopause. The majority of spironolactone is eliminated by the kidneyswhile minimal amounts are handled by biliary excretion.

Thank you for the time!! Larry Jameson; Leslie J. International Drug Price Indicator Guide. I feel i need to get my estrogen at a good level, yet everything i read for melasma acnw its caused by estrogen, i dont have high estrogen! Outputs of searches were imported into Rayyan to facilitate sorting [ 25 ], and full-text copies of all potentially eligible studies were obtained. Im not on the pescription iron which is even higher. Let it just naturally do whatever it is going to do instead of messing with it all so much.


I am so tired of being sick like this times a month since the summer.

Profile of acne vulgaris: Evidence for lower doses with respect to comparative efficacy versus placebo or active comparators was equivocal and of low or very low quality. If I cease taking whatever sparked the reaction, the shedding reduces significantly within a day or two.

If Id known refined sugar and dairy were the problem I would have preached this to my brother who went on accutane and is now spiraling down into depression.

Hirsutism associated with congenital adrenal hyperplasia or androgen-secreting tumor. I have not had zinc checked yet. Sign up for a new account in our community.

Thankfully I knew these thoughts were irrationally but it was soooo scary! Oxford Textbook of Medicine. Espifonolactona spironolactone was developed nearly 30 years ago, the scientific study of aldosterone was limited to effects on epithelial ion transport, and even this knowledge was espirnolactona its infancy.

Furthermore, in the study by Saint-Jean et al. Im am thin, so i know i dont make much estrogen, its hard for me to put weight on and keep weight on which bothers me.

This drug is a joke.