Evaluation of the Abbott RealTime HBV DNA Assay and Comparison to the Cobas AmpliPrep/Cobas TaqMan 48 Assay in Monitoring Patients with Chronic. This study is aimed to investigate whether there is drug-resistant strains related detection difference between Abbott RealTime HBV (RealTime). Korean J Lab Med. Apr;28(2) doi: /kjlm [ Performance evaluation of Abbott RealTime HBV Quantification Kit for HBV viral.

Author: Gugor Disida
Country: Saudi Arabia
Language: English (Spanish)
Genre: Music
Published (Last): 2 October 2017
Pages: 310
PDF File Size: 9.19 Mb
ePub File Size: 10.17 Mb
ISBN: 615-8-55938-388-5
Downloads: 49437
Price: Free* [*Free Regsitration Required]
Uploader: Nirn

A total of specimens were included in this study: Hepatitis B induced by HBV is a serious health problem. Because of the central metabolic role of the liver, we assessed the metabolic impact of HBV infection as a means to identify viral dependency factors and metabolic pathways that could serve as novel points of therapeutic intervention.

The difference in the rate of transmission depends on the prevalence of the infection; mother-to-child or child-to-child transmission is higher when compared to IV drug use and high-risk sexual activity. Greater flexibility in sample processing is a critical factor that can improve the time to results while reducing reagent waste, making laboratories more efficient and cost-effective. In conclusion, the Aptima HBV Quant assay is sensitive, specific, and reproducible and accurately quantifies HBV DNA in plasma samples from patients with chronic HBV infections of all genotypes, including patients on antiviral treatment with nucleoside or nucleotide analogues.

Therefore, HBV can be transmitted to other patients via contaminated environmental surfaces or quilts, resulting in an HBV nosocomial infection. For the Abbott i, realtim coefficients of variation CV for the low, medium, and high concentration samples ranged from 1.

Real-Time Hepatitis B Virus Assay

HC2 showed a sensitivity of Patients were divided into the antiviral treatment group and the no-antiviral group. The sample consisted of individuals belonging to 38 populations collected between and While significant advances in the treatment of cancer occured during the last half of the twentieth century, parallel decreases in overall cancer death rates were not observed.


The Bland-Altman plots were used for the analysis of agreement between the two assays. Liver Rapid Reference Set Application: Serum hepatitis B xbbott HBV markers are the most important data for epidemiological screening and clinical diagnosis of HBV infection, especially in endemic areas.

abbott realtime hbv: Topics by

Tubulointerstitial nephritis should be considered as a part of the differential diagnosis in patients with HBV infection. The gold-standard assay was histopathological confirmation of cervical intraepithelial neoplasia of grade 2 or worse. EASL clinical practice guidelines: This study would like to evaluate its performance.

Using conventional culture results and clinical background as reference standards, Abbott -RT exhibited an overall sensitivity and specificity of The need for viral load VL monitoring of HIV patients receiving antiretroviral therapy ART in resource-limited settings RLS has become apparent with studies showing the limitations of immunological monitoring.

The ongoing debate concerning the efficacy of fenofibrate has overshadowed an important aspect of the drug’s history: Two main groups of Mobil Oil Indonesia population namely “employees” and “dependents” were also included in this study. Through a series of indicators, the Camden Abbott Indicators Report presents the status of educational….

Accessed February 10, Japanese phase II trials were expected to commence in June and a phase II trial is being designed for respiratory infections, with Abbott expecting filing in March [].

Real-Time Hepatitis B Virus Assay

Previous studies reported that hepatitis B virus HBV deoxyribonucleic acid DNA can be detected in livers of patients who received transplants for hepatitis B despite the absence of serological markers of HBV recurrence.

Despite the large number of studies for HBV integration into liver cancer, little is known about the mechanism of initial HBV integration events owing to the limitations of materials and detection methods.

Validation was further performed in an expanded cohort of human Abbotg. In addition, agreement between the Roche assay and the Aptima assay abboft specimens with low.


Nine chlorogenic acid analogues were detected from the active part Fr. HCV genotyping remains a critical tool for guiding initiation of therapy and selecting the most appropriate treatment regimen. Thus, compared to other parts of India, the molecular epidemiology of HBV is naturally distinct in eastern India. In the United States, rates appear to be highest in males ranging from 25 to 44 years of age, and in African Americans, Hispanics, and those of Asian descent.

Plus assay and sequencing results were concordant for All patients were negative abbot HBsAg. This current study focused on its anti- HBV active constituents by various chromatographic methods. The second series was routed by mail and tested after up to 3 months of storage at ambient temperature. Within-run and between-run coefficients of variation CV were 3.

We show that HBV is prone to integrate into rare fragile sites and functional genomic regions including CpG islands. Therefore, murine restriction factors that limit HBV infection need to be identified before a HBV -permissible mouse line can be created. Phylogenetic analysis showed the divergence of HBV sequences, between mono- and co-infected patients, into two distinct clusters.

The Plus assay and sequencing were applied to 98 of those samples. The analytical sensitivity, analytical specificity, precision, and linearity of the Aptima assay were assessed. This panel of biomarkers should perform significantly better than alpha-fetoprotein AFP alone based on multivariate statistical analysis.

A cross-sectional study of prevalence and awareness of hepatitis B and hepatitis B vaccine was conducted among randomly selected physicians and nurses employed in seven hospitals in Georgia in and At low VLs 0.